TCS 1102

CAS No. 916141-36-1

TCS 1102 ( TCS 1102, TCS1102, TCS-1102 )

Catalog No. M17659 CAS No. 916141-36-1

TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).

Purity : 97%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 51 In Stock
10MG 81 In Stock
25MG 158 In Stock
50MG 291 In Stock
100MG 408 In Stock
500MG 945 In Stock
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Biological Information

  • Product Name
    TCS 1102
  • Note
    Research use only, not for human use.
  • Brief Description
    TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
  • Description
    TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). TCS 1102 inhibits ADL-orexin B-mediated locomotion following i.p. administration in vivo and blocks orexin-A (Cat.No.1455) mediated increases in feeding behaviour.
  • Synonyms
    TCS 1102, TCS1102, TCS-1102
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    OX1; OX2
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    916141-36-1
  • Formula Weight
    470.59
  • Molecular Formula
    C27H26N4O2S
  • Purity
    97%
  • Solubility
    DMSO : ≥ 100 mg/mL; 212.50 mM
  • SMILES
    Cn1c2ccccc2nc1SCC(=O)N1CCC[C@H]1C(=O)Nc1ccccc1c1ccccc1
  • Chemical Name
    (2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bergman JM, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1425-30.
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