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TCS 1102
CAS No. 916141-36-1
TCS 1102 ( TCS 1102, TCS1102, TCS-1102 )
Catalog No. M17659 CAS No. 916141-36-1
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
Purity : 97%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 51 | In Stock |
|
| 10MG | 81 | In Stock |
|
| 25MG | 158 | In Stock |
|
| 50MG | 291 | In Stock |
|
| 100MG | 408 | In Stock |
|
| 500MG | 945 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTCS 1102
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NoteResearch use only, not for human use.
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Brief DescriptionTCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
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DescriptionTCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). TCS 1102 inhibits ADL-orexin B-mediated locomotion following i.p. administration in vivo and blocks orexin-A (Cat.No.1455) mediated increases in feeding behaviour.
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SynonymsTCS 1102, TCS1102, TCS-1102
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PathwayAngiogenesis
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TargetCDK
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RecptorOX1; OX2
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number916141-36-1
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Formula Weight470.59
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Molecular FormulaC27H26N4O2S
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Purity97%
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SolubilityDMSO : ≥ 100 mg/mL; 212.50 mM
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SMILESCn1c2ccccc2nc1SCC(=O)N1CCC[C@H]1C(=O)Nc1ccccc1c1ccccc1
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Chemical Name(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bergman JM, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1425-30.
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